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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fd3de81c482256f8b93b8659ebc5dd3a791403e2e8afcf08e4c3b47d0b49ecc' 
  AND token = 'n2fELaJi/hqP1PcZZwq8+PvbYFUmqfdpbJU0lFeY7dw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}