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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e298b097935d91fae3948c82d459ba0134c46770c7cf9a6ca7017e193b0271' 
  AND token = 'SmTbgEtS5yRlaW6nJn0iL11VF2BOZztCZ9FRyx/sAAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}