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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bce6541cef4c05291256ad3350b9397403ed354e12a039005b5ee6ec3b116d5' 
  AND token = 'cQt5iFpvKFY+29ipg/o+7S3wU6nU0I0E6R0fPFeIt8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}