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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb77879ff7471c5b53893153338e9e78cb4bc3971584d8b559af388a576ab7f' 
  AND token = 'sIS43ME9Kka8DhZ2pfKEpgKvSQqTXq25H7XXqmYKlh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}