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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ac35d05be557b14f4933147ec2f8290dbdc1073a722ce26f607bfd569ab964' 
  AND token = 'LkN3/dZAyekNxwMzyoRsFTz0I/Cqmcm/3rEx7T9qtNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}