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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539efda01e62fb3c3a333447f16f649005aeefe94e663e41822de5e057d1b2bf' 
  AND token = 'zFzey9hABVNfdz7lDgxqbA1HDcbAKOicQQPGiGcYJ1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}