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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b12557814eababacaffd1fc64ee600822b27a27b9a3c0939b24238db176fda3' 
  AND token = 'Smn7xlOBta8k2gPxtXe759F14wTjHO2md0CN+4f23to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}