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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a12eced930b82dcf7ba9ff244f9580a7c1ba20f23c323e424f431e433fd92fd9' 
  AND token = 'OPd8z64o80CIS9Q5DUof+myNAqqAVHf4dCuL7C9Wlow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}