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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074e9cf8f68fc0ab6ebdc1b732172892aa07326304dc76029200fa46ad564890' 
  AND token = 'OXKr0HVliLZ/4jlV7BoIoPRcroSPxtefE77wyncTXdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}