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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ecee70b0eb75409259f8c985ce4585bc4f695b985e64b78bcac631bfef3d030' 
  AND token = 'u0qcUyEK2sNLK6VhjMFlA2gavlB3QDJ8cumdWBMaD+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}