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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '625878a02ba23d82d7273f79fe7299d907fc7093916c04275c1d92126f780333' 
  AND token = 'EIUO8TzFH63Uoc7J1GXwhYGmEC6/rmbuUmE8WkFaOmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}