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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44301b425d841a5d7e0413b412e603075bab3a7184f26ff236eb229b21e97dc3' 
  AND token = 'nl5POqoMasxm0K7XHL4B5pwKxSKTC9LCRHIe7fe6JOY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}