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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e84e61651d05e1413af43b930cae114331e949592bbd6fc2220a5003c775c00' 
  AND token = 'xqey39yL/GfmMFkwP7W6RUm+RLTT/R5ziRvwTvBjdCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}