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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b64309a209beb14b075b883cd3bbc1e0d12aaf1576927451aa2bfa39fdef01df' 
  AND token = 'wRFYBBoK/T20/v5ELnvpVL1zi4gg7yPLxWT5w1gz01U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}