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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ceb1283abd7fc8906010db774ca88e92335ef023cf81e716e189a4e5b0a5296' 
  AND token = 'o/Ft2Q4eBqkhhQZDdz9i7SW6SSe29JwCb/v6cLeoy7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}