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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '150143f66c56a50dc3197df8d45511966be2c8caee670f84b71086b926155fb0' 
  AND token = 'ezczcx1eqbpYICx7Neo2wezbR4i8DKQ8P4+BUP+nzWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}