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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a28c01c902021e160a72d171838392da2a3cf6a59711e05ad6b4a94269b021e8' 
  AND token = 'zjbTLBH94bJJbF+wxRpwyvErN4V1ehOyRgn5Bg5qzT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}