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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17fd546aed6d67f34c6560c174d2bb35b9fc87e5494747ee22bcf3ff883bc2f2' 
  AND token = 'nN0dvW1PT5w/Y4a5wg0uDLalpcHoFqXyaViXXRBXvTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}