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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5313728b00dce476d09866523fcaadf57b8e71464e7e60788edcc4f616da0c7' 
  AND token = 'U0NxvM7efi5r43boUMsEeR1pbkMU3GeaGFGPNxcI+e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}