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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bca7a4e0abb24db923ccd3f8a79004cc6c47706998c6be0d211079888402bc9d' 
  AND token = 'hM5mmYVW8Rc37D9dC2PAUyUKevY5XIcsRC2oDQcyL5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}