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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5459e24010b3591c96d73eaf47110495278b11bc191d58eb12698def23b322a' 
  AND token = '0fPJW7l+1+ZgiWRlaiqQLdMzeGaPq0qCRjeDJ1TG9iQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}