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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e91c44e4bb69b456e9cf5b5f100bc4421aa882ba7d771255633e60f8c2b2a45d' 
  AND token = 'nJax7XxhysK58D1q9UmPcgayHIu6VDEhj19dqDTR53E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}