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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7aaf826a9903ec1a1fe3c1db55e9689b2ddfc32fb3648bd978d2992c0ec450' 
  AND token = 'hwxHBA3qQjMWEL5q312X7WEnhnJpHjskYTkwCa5hmHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}