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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0b6a99a560c2cfcbad351d6d2966de53ecf6f81912087daaa039b907df7b82' 
  AND token = 'yWm6UcXRzAhZAj7JfEvrFhZlY//rekK8GSXcNQ+MaUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}