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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b074f8fe5a2233c2b8a23fb12d853d72241c9b851a18cebb44f033b8f8b19fe' 
  AND token = '6UeQlrWxmbxeDzuygTw5bSsoyKmE4I0YZ6ChFBUGmTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}