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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc6f112e202251c31040b484a0e678a4d8fc413e588784253bd268463ecb1f69' 
  AND token = '0+0lEr2O7tnzZGOCCSMv+ndmyGhqRSDeUG3Hb9Y2Yjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}