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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc7e17f750018553d887e39b45fffc9abecd881d6e4f0249cad698e672df7ccb' 
  AND token = '2FdXFmIrgXEjvi4V+VNoE7QUcLifonYrYMySjkEP2ts=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}