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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a41a4de6592441801e091368664576c3d141be2d8f85b099766e5b72aedf49a' 
  AND token = 'kCq50uGUVFW/wVg5nqjkEbRZcwi2r11u/BtMRJd1OGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}