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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c166da9c4daca3c4710d64379b933fcc9827476322196fc65e8a5ddf63dc836' 
  AND token = 'QYM91xRkQyBGGtnUwckVDcWN+kw/pqWZkd0E1dKqmLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}