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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deedbb4f512bda4347ac269a8a7c380191863442cc19737b450f677a190df10d' 
  AND token = '6uVfk6hSDhKMtQ9sXmF5cKvhLYVA9b7+9gT2aKbBsto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}