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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66cddf1493a7d4dcd390fcbaffa879067508552a61227fb3d22ed224bd9f8671' 
  AND token = 'seG1yx+q/5Ey3Iz2qmm+YG9zZm3Uk3xWYkOsy69IWaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}