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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e1180a7ecdc8ca9a53a3f63020a3ff8cdc1df3029366406650bee268ef16b61' 
  AND token = 'MbHJtOn3vvBRmCVd5mESYI2a8B15Yaekw63A1khAsn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}