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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd499ac78bb745b65576ab033b5b1aeaccf17a21dbe5499aed676b5a7038f72e4' 
  AND token = 'MzS8t2WeAW/oDLPfQThg18oKjb/B0aSzUFQzRVeahoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}