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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427b341d3fdac1f3333b5f9c79f22a5939ca78f32f6f6bf1898203045b96fb26' 
  AND token = 'i2y8xsVUQb8+85YnQ0nz6zJ9lUafIxLxl6P6FhJhMRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}