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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d6b343dad296c85b258c8f08da30550a52497e405f1e002cdab1e101a981113' 
  AND token = 'JncGpXMD6C06xcqXgCYvH294kO8WXvL8Hkig7uW93ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}