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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a12e2a93b9cfb60bcc5ced562cede99f45481dd62328182c14cf554b5b65665' 
  AND token = '0DcgmTOxu0h2jg6MUGDjBuHfd63qX0ZSxef2dh/LXP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}