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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b72a6b02dbb525172e7c22f36d8d6fc70c2e14c150b4d283e5f6b38741553f5' 
  AND token = 'dFsRuYiTkuU1u1Cgvom3vcK+BmmF7yry36m1CnxgdYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}