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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9caa29377b9a8c6bdee53db68c0ad657d72ee1c88e8dd92b31db9341088e2bd' 
  AND token = 'mVxpzIIq5lA9A3inqLQNn9L6B6PwVVLxqYaaHKMa/fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}