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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d20fc4d1f8f8a648e9c49ee97f7a1fb7684f6d85256f25d5e580752ad175f52' 
  AND token = 'umJTJZJHeCoPT0bHsGt/OjHEos7DvnY9ZxPGe10wFSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}