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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c64eb6a04c3a81f422fd428afe758059912b937650e0e5e5fdd2051840ccc882' 
  AND token = 'ET+ZxizOGR9C0dYUzG3H6ebUoD6kltJ74ijJRYl2bsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}