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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8718c28f14dbca220dce72ff6622644452e815abdc9fd20fd76a21c4bab00ddb' 
  AND token = 'Et4TONJvZzEmNskmMxLph5dUe4WBQPBq490A2qc3/b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}