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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f5e9b521d9e775feff10a7c149d6409b4e5f58494f4fdabc588607f0b4af99' 
  AND token = 'jFDOrxiQD1Zzoqivtu121Z1L5VEdVygxmXHYFI2TCdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}