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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5c7cb105895a6906184dd2a364686d115539905d5e9ee4b22d3ac251c7a787' 
  AND token = 'nXv9UugNr9XdA889OdN7JsRCAB3ejL6kMFPTuEfUe20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}