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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b71cd911bde0b8415454b597365f2a7b67e65d5dc30a43c8f760045306491400' 
  AND token = 'f8nz9AzPGqtMbRkzqklNDaTq7PX4PeeZ203/PsMoz2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}