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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f1b0c71e419eec01490f5fdd03b8ab1669da1ac20ee76fb65e8681197bb652' 
  AND token = 'BYzX/I+kKUBHrrqF+uRDu4zpP22BSa0eR30KrZP20gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}