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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1dfeea52cf41153ced933b49a2a39208ef74689813cb6641e5b880e7e9f49d0' 
  AND token = 'axJOaQNEn579NAyeU+NA/xBeEtBqn5684f3FY6H6nDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}