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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fd92d8617c14d6fd76201475e6036212bb579cd26e0cce71bc5723ad6211e55' 
  AND token = 'UQp7T5rQQrp+zEo+HPylTiN0kpGlVlJ9C/0oUHzcnsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}