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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81aa8966ac45f1a0a69f086750db0ee1c254c2a082525771b902cd11e26cc785' 
  AND token = 'TYx/1lIhGI2zw478dXdXco8nPWn82TKvQ7lZFbQdKhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}