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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e2e6a2807bdea45b9891e0d1b39e3beef70669d29728e8f47652ba3f0bb44a7' 
  AND token = 'E4nNBZjIlkq1dTGbbWlIvcf1uTIAHEZub2W/AI3P2DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}