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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4952835bea54d8122339ccab6e84c45714b9e2ae76ff0c123c567b7e0e0a0fd0' 
  AND token = '7i+HUMT1DVUYy2TjFT8yFeAWRHOlalwaPCn7Gy6Ku70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}